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Contraindicated (1)pentobarbital will reduce the level or effect of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with strong CYP3A4 inducers can result in lessened serum concentrations and loss of antimalarial efficacypentobarbital will decrease the level or effect of vinorelbine by affe